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Christopher Pittenger Selected Research

Histidine Decarboxylase

1/2020The histidine decarboxylase model of tic pathophysiology: a new focus on the histamine H3 receptor.
11/2018Striatal Signaling Regulated by the H3R Histamine Receptor in a Mouse Model of tic Pathophysiology.
1/2017Histidine Decarboxylase Knockout Mice as a Model of the Pathophysiology of Tourette Syndrome and Related Conditions.
1/2017Histamine modulation of the basal ganglia circuitry in the development of pathological grooming.
5/2015Histidine decarboxylase knockout mice, a genetic model of Tourette syndrome, show repetitive grooming after induced fear.
1/2014Histidine decarboxylase deficiency causes tourette syndrome: parallel findings in humans and mice.

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Christopher Pittenger Research Topics

Disease

20Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
01/2022 - 09/2005
7Tourette Syndrome (Tourette's Syndrome)
01/2020 - 01/2014
6Tics (Tic)
01/2020 - 01/2014
4Mental Disorders (Mental Disorder)
01/2022 - 01/2005
3Tic Disorders (Tic Disorder)
01/2020 - 01/2016
3Trichotillomania
03/2013 - 01/2007
2Schizophrenia (Dementia Praecox)
01/2021 - 01/2016
2Neurodevelopmental Disorders
01/2021 - 01/2019
2Inflammation (Inflammations)
10/2016 - 06/2008
2Nausea
08/2015 - 01/2008
2Bipolar Disorder (Manic Depressive Psychosis)
07/2013 - 01/2008
2Major Depressive Disorder (Major Depressive Disorders)
07/2013 - 04/2007
2Anxiety Disorders (Anxiety Disorder)
06/2011 - 01/2008
2Alzheimer Disease (Alzheimer's Disease)
11/2010 - 06/2008
2Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2008 - 01/2006
1Autism Spectrum Disorder
01/2021
1Telomeric 22q13 Monosomy Syndrome
01/2021
1Parkinson Disease (Parkinson's Disease)
01/2019
1Dyskinesias (Dyskinesia)
01/2019
1Alcoholism (Alcohol Abuse)
01/2017
1Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
01/2016
1Disorders of Excessive Somnolence (Hypersomnia)
01/2016
1Narcolepsy
01/2016
1Seizures (Absence Seizure)
03/2015
1Respiratory Insufficiency (Respiratory Failure)
07/2013
1Mood Disorders (Mood Disorder)
06/2011
1Dementia (Dementias)
06/2008
1Alcohol Withdrawal Delirium (Delirium Tremens)
03/2007
1Excoriation Disorder
12/2006
1Hallucinations (Hallucination)
04/2006
1Borderline Personality Disorder (Personality Disorders, Borderline)
11/2005

Drug/Important Bio-Agent (IBA)

9Glutamic Acid (Glutamate)FDA Link
07/2017 - 11/2005
8RiluzoleFDA LinkGeneric
08/2015 - 09/2005
6Histamine (Histamine Dihydrochloride)FDA Link
01/2020 - 01/2016
6Histidine DecarboxylaseIBA
01/2020 - 01/2014
4Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
07/2017 - 01/2006
3Acetylcysteine (Siran)FDA LinkGeneric
07/2017 - 01/2006
3KetamineFDA LinkGeneric
01/2017 - 12/2012
2Proteins (Proteins, Gene)FDA Link
01/2021 - 06/2008
2Pharmaceutical PreparationsIBA
01/2019 - 01/2008
2Histamine Receptors (Histamine Receptor)IBA
11/2018 - 01/2016
2EnzymesIBA
01/2017 - 01/2017
2Dextroamphetamine (Dexedrine)FDA LinkGeneric
05/2015 - 01/2015
2Dopamine (Intropin)FDA LinkGeneric
01/2014 - 06/2011
2N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
07/2013 - 04/2007
1Hallucinogens (Psychedelics)IBA
01/2022
1Histamine H3 Receptors (Histamine H3 Receptor)IBA
01/2020
1Levodopa (L Dopa)FDA LinkGeneric
01/2019
1AntioxidantsIBA
07/2017
1Nonsense Codon (Nonsense Mutation)IBA
01/2017
1pitolisantIBA
01/2016
1Pharmacologic ActionsIBA
01/2016
1PicrotoxinIBA
03/2015
1GABA-A Receptors (GABA(A) Receptor)IBA
03/2015
1MuscimolIBA
03/2015
1Dopamine Agents (Dopaminergic Agents)IBA
01/2015
1Cholinergic Agents (Cholinergics)IBA
01/2015
1Haloperidol (Haldol)FDA LinkGeneric
01/2014
1Hypnotics and Sedatives (Sedatives)IBA
07/2013
1Antidepressive Agents (Antidepressants)IBA
07/2013
1IGF-I-IGFBP-3 complexFDA Link
06/2011
1GoldIBA
06/2011
1Tyrosine (L-Tyrosine)FDA Link
11/2010
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
11/2010
1Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA
09/2008
1Amyloid beta-PeptidesIBA
06/2008
1Transforming Growth Factors (Transforming Growth Factor)IBA
06/2008
1CytokinesIBA
06/2008
1Transforming Growth Factor beta (TGF-beta)IBA
06/2008
1Transforming Growth Factor beta Receptors (TGF beta Receptors)IBA
06/2008
1Amyloid (Amyloid Fibrils)IBA
06/2008
1Amino AcidsFDA Link
01/2008
1Clomipramine (Anafranil)FDA LinkGeneric
10/2007
1Gabapentin (Neurontin)FDA LinkGeneric
03/2007
1Bupropion (Wellbutrin)FDA LinkGeneric
04/2006
1Memantine (Namenda)FDA Link
04/2006
1Biological ProductsIBA
01/2005

Therapy/Procedure

7Therapeutics
01/2021 - 09/2005
5Drug Therapy (Chemotherapy)
01/2021 - 01/2005
2Transcranial Direct Current Stimulation
01/2022 - 11/2021
1Neurofeedback
01/2014
1Off-Label Use
07/2013
1Anesthesia
07/2013